Report summary：Compartmentalization is the most important feature in living organisms, best seen in plant or animal cells, where different compartments have different functions. We aim at mimicking nature in synthesizing multicompartment micelles, which simultaneously can host different payloads, such as drugs or magnetic or fluorescent nanoparticles. The self-assembly of ABC triblock terpolymers in solution and in the bulk are ideally suited for such a task. Here we present a flexible route for the hierarchical, guided self-assembly of triblock terpolymers into multicompartment micelles (MCMs) of different shapes and sizes, simply by choosing the right solvent conditions and solvent sequences. These MCMs can have spherical shapes, like hamburgers, clovers, or footballs, or they reversibly form worm-like structures with
alternating compartments. The different compartments can be loaded with various nanoparticles or drugs. Eventually, we present a systematic approach to combine particle geometries with internal morphology and thereby establish a library of so far unprecedented nanostructures.